کروتامیتون

کروتامیتون
داده‌های بالینی
AHFS/Drugs.commonograph
رده‌بندی داروهای
بارداری
کد ATCvet
شناسه‌ها
  • (E)-N-Ethyl-N-(2-methylphenyl)but-2-enamide[۱]
شمارهٔ سی‌ای‌اس
پاب‌کم CID
دراگ‌بنک
کم‌اسپایدر
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.907 ویرایش در ویکی‌داده
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC13H17NO
جرم مولی203.28 g/mol g·mol−1
مدل سه بعدی (جی‌مول)
  • O=C(N(c1ccccc1C)CC)/C=C/C
  • InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+ ✔Y
  • Key:DNTGGZPQPQTDQF-XBXARRHUSA-N ✔Y
 N✔Y (این چیست؟)  (صحت‌سنجی)

کروتامیتون (به انگلیسی: Crotamiton)دارویی است که برای درمان گال و درمان خارش استفاده می‌شود.

رده درمانی: عوامل موضعی پوستی

اشکال دارویی: پماد

مکانیسم اثر

مکانیسم ضد خارش آن ناشناخته است ولی اثر آن عمومی است و کانال یونی TRPV4 را مهار می‌کند. کروتامیتون برای مایت (انگل جرب) توکسیک است.

عوارض جانبی

واکنشهای آلرژیک، تحریک و التهاب پوستی .

منابع

  1. Crotamiton at alanwood.net
  • فرهنگ داروهای ژنریک ایران، دکتر حشمتی ، ۱۳۸۷

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