MISE EN EVIDENCE D'UNE MORT CELLULAIRE PROGRAMMEE (APOPTOSE) DU MYOCYTE CARDIAQUE DANS LA DYSPLASIE VENTRICULAIRE DROITE ARYTHMOGENE (DES PATHOLOGIE CARDIOVASCULAIRE) (1996)
Ziad Mallat is a French cardiologist. As a professor of Cardiology at the University of Cambridge, Mallat was the first to identify a major atheroprotective role of regulatory T cells and associated anti-inflammatory cytokines, IL-10 and TGF-β.
Mallat was the first to identify a major atheroprotective role of regulatory T cells and associated anti-inflammatory cytokines, IL-10 and TGF-β. Later, he identified selective pathogenic and protective roles for defined B cell and innate lymphoid cell subsets in atherosclerosis and cardiac remodeling following ischemic injury.[1]
During the COVID-19 pandemic, Mallat's research team was shortlisted by the British Heart Foundation for their £30m research prize for his project iMAP. The aim of his proposal was to create a "Google map" of human atherosclerosis.[2][3] On May 13, 2020, Mallat was one of six faculty members elected to the Academy of Medical Sciences.[4] He was elected for having made "sustained and internationally recognised contributions to our understanding of cardiovascular immunology and atherosclerotic disease and translated these novel findings into clinical trials."[5]
