In 1902 she became a teacher at Dagteeken- en Kunstambachtsschool voor Meisjes (Day drawing and craft school for girls) where she worked until 1908. Drupsteen worked as an illustrator for the Dutch women's movement and other social organizations. She also provided illustrations for the magazine Maandblad der Vereeniging voor Verbetering van Vrouwenkleeding.
In 1913 Drupsteen created the poster for De Vrouw 1813-1913. The image also used for the cover of the exhibition catalog.[3]
Suffering from physical and financial problems, Drupsteen moved from Amsterdam to Gelderland, eventually settling in Oosterbeek. By 1955 she was no longer able to work due to failing eyesight.[3] Drupsteen died on 2 April 1966 in Oosterbeek.[2]
