W17AI began broadcasting in 1987. It was owned by Regional Broadcasting Corporation, owned by Gary and Susan Clarke; beginning in 1988, it primarily served to rebroadcast WWAT-TV in Chillicothe. At the time, WWAT-TV had been removed from all three of the cable systems in the Columbus area.[2][3] This was a change from Clarke's original plan for programming W17AI after he purchased the permit from the LaMarca Group of New York City the year before; he had originally intended on programming oriented to the large campus audience at Ohio State University.[4][5] The Clarkes sold the station in August 1989 to WWAT-TV owner Wendell A. Triplett.[6] In 1991, W17AI split from WWAT-TV to broadcast the Home Shopping Network.[7] The call sign was changed to WDEM-LP in 1998.
In early 2009, the station—still owned by Triplett—changed its programming from home shopping to an arts and culture format known as "Lifeline Columbus" under the leadership of David Chesnet.[8] The station had previously become a Class A station in December 2008, changing call signs from WDEM-CA to WDEM-CD.[9] The station also converted to digital in 2009 and added a subchannel airing Telemundo in 2010. Subchannels aired in the 2010s included Universal Sports and Justice Network (now True Crime Network). Minority Brands, owned by Richard Schilg, acquired WDEM-CD from Triplett for $75,000 in 2014.[10]
On April 3, 2019, HC2 Holdings closed on its acquisition of WDEM from Minority Brands, Inc., for $866,000.[11] The station then moved from channel 17 to channel 24 as part of the repack, with Telemundo replaced by HC2-owned Azteca América.