Vsetín District borders Slovakia in the southeast. The terrain is hilly to mountainous and except in the northwest, most of the landscape is forested. The territory extends into seven geomorphological mesoregions: Hostýn-Vsetín Mountains (most of the territory), Maple Mountains (southeast), Vizovice Highlands (southwest), Rožnov Furrow (a strip in the north), Moravian-Silesian Beskids (north), Moravian-Silesian Foothills (northwest), and White Carpathians (a small part in the south). The highest point of the district and of the entire Zlín Region is the mountain Čertův mlýn in Prostřední Bečva with an elevation of 1,206 m (3,957 ft). The lowest point of the district is the river bed of the Bečva in Kelč at 263 m (863 ft).
From the total district area of 1,131.1 km2 (436.7 sq mi), agricultural land occupies 403.0 km2 (155.6 sq mi), forests occupy 620.9 km2 (239.7 sq mi), and water area occupies 11.1 km2 (4.3 sq mi). Forests cover 54.9% of the district's area.[1]
The most important rivers of the district are the Vsetínská Bečva and Rožnovská Bečva, which join in Valašské Meziříčí and create the Bečva River. The area is poor in bodies of water. The only notable bodies of water is are the Karolinka and Bystřička reservoirs.
There are no motorways passing through the district. The most important road is the I/35 (part of the European route E442 from Olomouc to the Czech-Slovak border.