On 23 June 2021, Ekpai signed for Czech champions Slavia Prague, following the expiry of his contract with Viktoria Plzeň.[7] On 21 January 2022, as part of the deal to sign compatriot Yira Sor, Ekpai was loaned to follow Czech First League club Baník Ostrava.[8] On 25 August 2022, Ekpai was loaned to follow Czech First League club Mladá Boleslav.[9]