Talk:Enolase
The article says human has 5 isozymes of enolase, while it lists only 3. CopperKettle 11:05, 14 May 2007 (UTC)Reply
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5 of 3 isozymes?
The article says human has 5 isozymes of enolase, while it lists only 3. CopperKettle 11:05, 14 May 2007 (UTC)
- I searched on Google Scholar, and most results talk of 3 isozymes (although they do not say if there are only 3 or if there are more). And this source from 1983 talks about 4 forms: alpha alpha, beta beta, gamma gamma and alpha gamma. Will check some textbooks too. - TwoOars 22:26, 20 August 2007 (UTC)
Merge with Phosphopyruvate hydratase
Enolase and phosphopyruvate hydratase are synonyms (http://brenda-enzymes.org/php/result_flat.php4?ecno=4.2.1.11). The enzyme's function is uniquely described by its EC number. Phosphopyruvate hydratase seems to be more universal in scope, while this article is rather human-centric. The two should be combined into one article.134.169.106.141 (talk) 16:01, 1 July 2013 (UTC)
- Support merger under the name Enolase as that article is more developed. ComfyKem (talk) 17:31, 1 July 2013 (UTC)
- Done. 134.169.106.133 (talk) 13:40, 20 July 2015 (UTC)
Fluoride
The references provided do not support the claim that inhibition of enolase is responsible for the cariostatic effects of fluoride. One study source only describes the extent of water fluoridation in the US, and the other only shows in vitro inhibition of the enzyme by fluoride but does not claim that those concentrations would be achieved by consuming fluoridated drinking water. Most of the cariostatic effects of water fluoridation are believed to be through the formation of acid-resistant fluorapatite in enamel.141.209.57.178 (talk) 16:39, 12 July 2019 (UTC)
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