TMEM66

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Store-operated calcium entry-associated regulatory factor

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Store-operated calcium entry-associated regulatory factor

Senin, 2026-07-13 08:43:22

known as transmembrane protein 66 (TMEM66) is a protein that in humans is encoded by the SARAF gene. SARAF (TMEM66) is a negative regulator of the store-operated...

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STIM1

Minggu, 2026-08-16 09:41:46

STIM1 has been shown to interact with ORAI1, TMEM110 (STIMATE), SERCA, TMEM66 (SARAF), and STIM2. STIM1 mutations are associated with Immunodeficiency...

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Calcium release activated channel

Sabtu, 2026-06-20 09:26:04

Ca2+ inside the ER approaches an upper set point, another protein, SARAF (TMEM66) associates with STIM1 to inactivate the store-operated calcium channel...

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