Shanghai Innovative Research Center of Traditional Chinese Medicine

Shanghai Innovative Research Center of Traditional Chinese Medicine

Industry	Healthcare, Pharmaceutical, Information Services
Founded	2000
Headquarters	Shanghai, China
Products	SAPHRON TCM Database, Yuxintine
Number of employees	60
Website	www.sirc-tcm.sh.cn （English version unmaintained)

Shanghai Innovative Research Center of Traditional Chinese Medicine (SIRC-TCM; Chinese: 上海中药创新研究中心), also known as National Innovation Center of TCM Modernization in Shanghai (国家中药现代化（上海）创新中心), is a Chinese research institute focusing on herbal medicine discovery and natural product development. SIRC-TCM was founded in 2000 and is headquartered in Shanghai, China.^[1]

Products

• SAPHRON TCM Database (赛方中医药数据库)^[2]
• Youxinding (Yoxintine, S111), a formulation of 20(S)-protopanaxadiol^[a] in trial (phase II complete, phase III recruiting) for depression^[3][4]
• Gengshu'an Granules (更舒安颗粒), TCM formulation. Clinical trial for menopause symptoms approved by Chinese authorities, status otherwise unknown.^[5]
• Herbal dietary supplements LP01, DP04, CS05, CM12, QT01, AP01, Feng Yuan Capsule (丰源胶囊)^[2]
• TCM-derived pure compounds^[2]

References

1. The abstract of the phase II study made a typographical error in naming the substance. The correct name is given by the related studies found by the Synapse new drug database.

1. "Shanghai Innovative Research Center of Traditional Chinese Medicine".
2. "产品与成果" [Products and results]. www.sirc-tcm.sh.cn (in Chinese).
3. "Youxinding". synapse.patsnap.com.
4. Dong, Z; Shen, Q; Zhu, H; Yang, Z; Lv, J; Feng, R; Bai, X; Huang, G; Hu, Y; Pan, L; Zhao, G; Jia, W; Wang, X (14 November 2024). "Efficacy and safety of YOXINTINE for depression: A double-blinded, randomized, placebo-controlled, phase 2 clinical trial". Phytomedicine : international journal of phytotherapy and phytopharmacology. 136: 156204. doi:10.1016/j.phymed.2024.156204. PMID 39580994.
5. "上海中药创新研究中心". www.sirc-tcm.sh.cn.