Senkayi is the daughter of Abu Senkayi and Sunajeh Senkayi. Her family are from Butambala District in Uganda. Her father was an environmental scientist and worked at Texas A&M University as a research scientist from 1977.[1][2]
Senkayi joined the United States Environmental Protection Agency in 2007.[6] She works with local children in schools and colleges talking about the environment.[5] She initiated the EPAConverses with Students webcast, an opportunity for children to speak to scientists who worked on environmental protection on Earth Day.[7][8] Her research focuses on water quality protection and she is the Water Quality Division Quality Assurance Officer.[3] In 2017 Senkayi was awarded the Presidential Early Career Award for Scientists and Engineers for her "transformative" community outreach and research.[3][9]