STRBP

STRBP
Identifiers
Aliases	STRBP, HEL162, ILF3L, SPNR, p74, spermatid perinuclear RNA binding protein
External IDs	OMIM: 611138; MGI: 104626; GeneCards: STRBP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DMY
Gene location (Human)
Chr.	Chromosome 9 (human)
End	123,268,586 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	37,593,871 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; primary visual cortex; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; sperm; ; ganglionic eminence; ; endothelial cell; ; parietal lobe; ; postcentral gyrus; ; epithelium of nasopharynx;
	Top expressed in
	tail of embryo; ; lacrimal gland; ; genital tubercle; ; zygote; ; medial dorsal nucleus; ; olfactory epithelium; ; Rostral migratory stream; ; medial geniculate nucleus; ; spermatocyte; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; double-stranded RNA binding; protein binding; single-stranded RNA binding; RNA binding; microtubule binding; tubulin binding;
Cellular component	cytoplasm; microtubule cytoskeleton; nucleus; manchette;
Biological process	multicellular organism development; mechanosensory behavior; cell differentiation; spermatogenesis; spermatid development;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55342
	20744
	ENSG00000165209
	ENSMUSG00000026915
	Q96SI9
	Q91WM1
	NM_001171137; NM_018387; NM_001376106; NM_001376107; NM_001376109
NM_009261; NM_176932; NM_001355259; NM_001379314; NM_001379315;
	NM_001379316
	NP_001164608; NP_060857; NP_001363035; NP_001363036; NP_001363038
	NP_033287; NP_001342188; NP_001366243; NP_001366244; NP_001366245
	Wikidata
View/Edit Human	View/Edit Mouse

Spermatid perinuclear RNA-binding protein is a protein that in humans is encoded by the STRBP gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165209 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026915 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".

Schumacher JM, Lee K, Edelhoff S, Braun RE (May 1995). "Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules". The Journal of Cell Biology. 129 (4): 1023–32. doi:10.1083/jcb.129.4.1023. PMC 2120489. PMID 7744952.
Schumacher JM, Artzt K, Braun RE (July 1998). "Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice". Biology of Reproduction. 59 (1): 69–76. doi:10.1095/biolreprod59.1.69. PMID 9674995.
Coolidge CJ, Patton JG (March 2000). "A new double-stranded RNA-binding protein that interacts with PKR". Nucleic Acids Research. 28 (6): 1407–17. doi:10.1093/nar/28.6.1407. PMC 111047. PMID 10684936.
Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P (May 2001). "Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities" (PDF). Developmental Biology. 233 (2): 319–28. doi:10.1006/dbio.2001.0169. hdl:11858/00-001M-0000-0012-F717-7. PMID 11336498.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000165209 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026915 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".

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[5]

STRBP

References

Further reading

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