SAOUHSCs221

SAOUHSCs221 is a 108nt bacterial antisense RNA found by RNA-seq analysis in Staphylococcus aureus strain HG003 grown in rich medium,[1] strain JKD60008

SAOUHSCs221
SAOUHSCs221 antisense RNA
Predicted secondary structure and sequence conservation of SAOUHSCs221
Identifiers
SymbolSAOUHSCs221
Alt. Symbolsart200, STnc490
RfamXXXX
Other data
RNA typeGene; sRNA
DomainBacteria
PDB structuresPDBe

SAOUHSCs221 is a 108nt bacterial antisense RNA found by RNA-seq analysis in Staphylococcus aureus strain HG003 grown in rich medium,[1] strain JKD60008 [2] and strain NCTC8325.[3]

SAOUHSCs221 is expressed antisense to the IS200 transposase sequence, at the level of the 5’UTR sequence of the transposase ORF. Construction of this family only identified homologues in Firmicutes. However a small RNA named art200 (antisense regulator of transposase IS200) was also described E. coli and S. enterica (enterobacteria).[4]

References

  1. ^ Liu W, Rochat T, Toffano-Nioche C, Le Lam TN, Bouloc P, Morvan C (2018). "Assessment of Bona Fide sRNAs in Staphylococcus aureus". Front Microbiol. 9 228. doi:10.3389/fmicb.2018.00228. PMC 5826253. PMID 29515534.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Howden BP, Beaume M, Harrison PF, Hernandez D, Schrenzel J, Seemann T; et al. (2013). "Analysis of the small RNA transcriptional response in multidrug-resistant Staphylococcus aureus after antimicrobial exposure". Antimicrob Agents Chemother. 57 (8): 3864–74. doi:10.1128/AAC.00263-13. PMC 3719707. PMID 23733475.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Carroll RK, Weiss A, Broach WH, Wiemels RE, Mogen AB, Rice KC; et al. (2016). "Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus". mBio. 7 (1): e01990-15. doi:10.1128/mBio.01990-15. PMC 4752604. PMID 26861020.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Ellis MJ, Trussler RS, Haniford DB (2015). "A cis-encoded sRNA, Hfq and mRNA secondary structure act independently to suppress IS200 transposition". Nucleic Acids Res. 43 (13): 6511–27. doi:10.1093/nar/gkv584. PMC 4513863. PMID 26044710.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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