As a freshman in 2015, McCloud played in 12 games, catching 29 passes for 251 yards and one touchdown.[4] He missed three games due to a knee injury.[5]
In 2016, as a sophomore, McCloud played in 14 of Clemson's 15 games, missing one due to an ankle injury.[6] In those 14 games, he tallied 49 receptions for 472 yards and two touchdowns, helping
Clemson win the National Championship.[7]
As a junior in 2017, McCloud played in all 14 of Clemson's games, tallying 49 receptions for 503 yards and one touchdown. He also returned 25 punts for 303 yards and one touchdown.[8] After the season, he declared for the 2018 NFL draft.[9]
McCloud was drafted by the Buffalo Bills in the sixth round with the 187th overall pick in the 2018 NFL draft.[12] In Week 3, in a 27–6 victory over the Minnesota Vikings, he made his first professional reception and had a 13-yard punt return.[13]
On August 31, 2019, McCloud was waived by the Bills.[14]
Carolina Panthers
On September 1, 2019, McCloud was claimed off waivers by the Carolina Panthers.[15] He was waived on October 15, 2019.[16]
Buffalo Bills (second stint)
On October 17, 2019, McCloud was signed to the Bills practice squad.[17] In addition to serving as a wide receiver, McCloud served as the scout team quarterback, emulating the style of mobile quarterbacks the Bills face that week.[18] He signed a reserve/future contract with the Bills on January 6, 2020.[19] He was waived on July 27, 2020.[20]
Pittsburgh Steelers
On August 21, 2020, McCloud signed with the Pittsburgh Steelers.[21] McCloud signed a one-year contract extension with the Steelers on March 11, 2021.[22] McCloud became the Steelers' primary return specialist, returning 28 kickoffs for 646 yards and 29 punts with an average of 10.7 yards. He was named by Pro Football Focus on its All-Pro roster as a second-team return specialist.[23][24]
In 2021, McCloud led the NFL in total punt-return yards gained.[25] He recorded 39 receptions for 277 receiving yards on the season.[26]
San Francisco 49ers
On March 22, 2022, McCloud signed a two-year contract with the San Francisco 49ers.[27] On October 23, in Week 7 against the Kansas City Chiefs, McCloud scored his first career touchdown on an 8–yard pass from Jimmy Garoppolo.[28] McCloud finished the 2022 season with 14 receptions for 243 yards and one receiving touchdown to go with a rushing touchdown. He handled some kickoff and punt return duties on special teams.[29]
McCloud was placed on injured reserve on December 9, 2023.[30] He was activated on January 6, 2024.[31] He finished the 2023 season with 12 receptions for 135 yards while handling some kickoff and punt return duties.[32] The 49ers reached Super Bowl LVIII, but lost 25-22 to the Kansas City Chiefs. In the Super Bowl, McCloud had 1 catch for 19 yards.
Atlanta Falcons
On March 18, 2024, McCloud signed a two-year contract with the Atlanta Falcons.[33]
^Varley, Teresa (August 21, 2020). "Steelers sign McCloud". Steelers.com. Archived from the original on September 21, 2020. Retrieved October 17, 2020.