REPS1

REPS1
Identifiers
Aliases	REPS1, RALBP1, RALBP1 associated Eps domain containing 1, NBIA7
External IDs	OMIM: 614825; MGI: 1196373; GeneCards: REPS1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	138,988,261 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	18,000,903 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; right uterine tube; ; parotid gland; ; olfactory zone of nasal mucosa; ; anterior pituitary; ; ganglionic eminence; ; right hemisphere of cerebellum; ; Brodmann area 9; ; skin of abdomen; ; right frontal lobe;
	Top expressed in
	genital tubercle; ; tail of embryo; ; secondary oocyte; ; zygote; ; submandibular gland; ; spermatocyte; ; gastrula; ; primary oocyte; ; Rostral migratory stream; ; seminal vesicula;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; SH3 domain binding; protein binding; metal ion binding;
Cellular component	membrane; plasma membrane; clathrin-coated pit; cytosol;
Biological process	receptor-mediated endocytosis; membrane organization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	85021
	19707
	ENSG00000135597
	ENSMUSG00000019854
	Q96D71
	O54916
	NM_001128617; NM_001286611; NM_001286612; NM_031922
	NM_001111065; NM_009048
	NP_001122089; NP_001273540; NP_001273541; NP_114128
	NP_001104535; NP_033074
	Wikidata
View/Edit Human	View/Edit Mouse

RalBP1-associated Eps domain-containing protein 1 is a protein that in humans is encoded by the REPS1 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135597 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019854 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: REPS1 RALBP1 associated Eps domain containing 1".

Cantor SB, Urano T, Feig LA (1995). "Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases". Mol. Cell. Biol. 15 (8): 4578–84. doi:10.1128/mcb.15.8.4578. PMC 230698. PMID 7623849.
Yamaguchi A, Urano T, Goi T, Feig LA (1998). "An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1". J. Biol. Chem. 272 (50): 31230–4. doi:10.1074/jbc.272.50.31230. PMID 9395447.
Ikeda M, Ishida O, Hinoi T, et al. (1998). "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral". J. Biol. Chem. 273 (2): 814–21. doi:10.1074/jbc.273.2.814. PMID 9422736.
Xu J, Zhou Z, Zeng L, et al. (2002). "Cloning, expression and characterization of a novel human REPS1 gene". Biochim. Biophys. Acta. 1522 (2): 118–21. doi:10.1016/s0167-4781(01)00310-4. PMID 11750063.
Cullis DN, Philip B, Baleja JD, Feig LA (2003). "Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors". J. Biol. Chem. 277 (51): 49158–66. doi:10.1074/jbc.M206316200. PMID 12364336.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hu Y, Mivechi NF (2003). "HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo". J. Biol. Chem. 278 (19): 17299–306. doi:10.1074/jbc.M300788200. PMID 12621024.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Drake KJ, Singhal J, Yadav S, et al. (2007). "RALBP1/RLIP76 mediates multidrug resistance". Int. J. Oncol. 30 (1): 139–44. doi:10.3892/ijo.30.1.139. PMID 17143522.
Singhal SS, Singhal J, Nair MP, et al. (2007). "Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer". Int. J. Oncol. 30 (3): 717–25. doi:10.3892/ijo.30.3.717. PMID 17273774.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135597 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019854 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: REPS1 RALBP1 associated Eps domain containing 1".

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REPS1

References

Further reading

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