He was born at a farm in Vonsbæk parish in the Duchy of Schleswig. He graduated in 1857 from Jelling Statsseminarium in Vejle. He was employed at Flakkebjerg Institute from 1857-1859. In 1859, he became a school teacher at Ørslev in Zealand, where he studied the local flora. He was particularly interested in plants useful to agriculture and in plant pathogens. He was a prolific writer on these topics. He undertook meticulous studies of rust fungi.[2][3][4]
^Nielsen, P. (1877). "Bemærkninger om nogle Rustarter, navnlig om en genetisk Forbindelse mellem Aecidium tussilaginis Pers. og Puccinia poarum n. sp" [Notes on some rust species, in particular the genetic unity of Aecidium tussilaginis Pers. and Puccinia poarum n. sp.]. Botanisk Tidsskrift (in Danish). 10: 26–42.