PRMT3

2FYT, 3SMQ, 4HSG, 4QQN, 4RYL

PRMT3
PRMT3
Identifiers
AliasesPRMT3, HRMT1L3, protein arginine methyltransferase 3
External IDsOMIM: 603190; MGI: 1919224; GeneCards: PRMT3
Available structures
PDBOrtholog search: PDBe RCSB
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
2.1.1.319↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

10196

71974

Ensembl

ENSG00000185238

ENSMUSG00000030505

UniProt

O60678

Q922H1

RefSeq (mRNA)

NM_001145166
NM_001145167
NM_005788

NM_133740

RefSeq (protein)

NP_001138638
NP_001138639
NP_005779

NP_598501

Location (UCSC)Chr 11: 20.39 – 20.51 MbChr 7: 49.43 – 49.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene.[5][6]

Interactions

PRMT3 has been shown to interact with RPS2.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185238 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030505 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tang J, Gary JD, Clarke S, Herschman HR (July 1998). "PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation". The Journal of Biological Chemistry. 273 (27): 16935–45. doi:10.1074/jbc.273.27.16935. PMID 9642256.
  6. ^ "Entrez Gene: PRMT3 protein arginine methyltransferase 3".
  7. ^ Choi S, Jung CR, Kim JY, Im DS (September 2008). "PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex". Biochimica et Biophysica Acta (BBA) - General Subjects. 1780 (9): 1062–9. doi:10.1016/j.bbagen.2008.05.010. PMID 18573314.

Further reading

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