On 5 August 2011 Cissé played his first match as a professional, starting in a 0–1 away loss against Stade de Reims for the Ligue 2 championship.[4] He appeared in 19 matches during the campaign, as his side was relegated as dead last.
Dijon
On 19 July 2012, Cissé signed a two-year deal with Dijon, also in the second division.[5] On 7 March 2014 he scored his first professional goal, scoring the second in a 2–2 draw with AJ Auxerre.[6]
Rayo Vallecano
On 4 July 2015 Cissé moved abroad for the first time in his career, after agreeing to a three-year contract with La Liga side Rayo Vallecano.[7] Following limited first team opportunities, Cissé joined Belgian side Waasland-Beveren in January 2016 on loan until the end of the 2015–16 season,
making twelve appearances for the club and scoring once.[8]
Tours
On 15 July 2016, after reaching an agreement with Rayo Vallecano to terminate his contract, Cissé joined Ligue 2 club Tours FC.[9] Over the following season, Cissé made a total of 26 appearances in all competitions, and scoring once before being released by the club.[10]
Milton Keynes Dons
On 29 June 2017, Cissé joined English League One club Milton Keynes Dons on a two-year deal.[11] On 6 January 2018, Cissé scored his first goal for the club, the winning goal in a 0–1, third round FA Cup victory over Queens Park Rangers.[12] On 11 August 2018, Cissé scored his first league goal, a 90th-minute winner, in a 1–0 home victory over Bury.[13] After two seasons in which he made 68 appearances in all competitions and scored 3 goals, Cissé announced on 11 May 2019 he would be leaving the club at the end of the 2018–19 season.[14]
Gillingham
On 24 June 2019, Cissé joined League One club Gillingham on a free transfer effective from 1 July 2019.[15] He made his debut for the club in their opening fixture of the 2019–20 season, a 1–1 draw away to Doncaster Rovers.[16] He scored his first and only goal for the club in the next league fixture as they were defeated 1–2 at home to Burton Albion.[17]
He signed for League Two side Leyton Orient on a six-month loan deal on 17 January 2020 and remained with the club until the curtailment of the season due to the Coronavirus outbreak.[18]
He was released by Gillingham at the conclusion of the 2019–20 season, having only made 5 appearances for the club in all competitions.[19]
Leyton Orient
On 16 July 2020, Cissé joined Leyton Orient on a permanent basis, signing a two-year contract.[20]
Oldham Athletic
On 7 August 2021, Cissé departed Leyton Orient by mutual agreement, joining Oldham Athletic on a one-year contract.[21] Oldham confirmed at the end of the season that they would not be offering Cissé a new contract and he would be leaving the club.[22]
Eastleigh
On 27 June 2022, Cissé agreed to join National League club Eastleigh following his departure from Oldham.[23] He was released after one season at the club.[24]
Ebbsfleet United
On 26 June 2023, Cissé signed for newly promoted National League club Ebbsfleet United.[25]