First manor building in this place was built in the end of the 18th century. In the 19th century, the manor became property of the von Brimmer family and in the 1860s a new neo-Gothic building was built. It was one of the most impressive neo-Gothic buildings in Latvia. It was heavily damaged by fire in Revolution of 1905 and only partially restored after it. In the 1920s Odziena Manor was nationalized in accordance with Latvian Land Reform of 1920. The building has been abandoned since 1960.
In 2014 with the assistance of European Unionstructural funds, a brewery, Odzienas muižas alus, was started in the mill-bakery of the manor.[3] Besides the brewery, a small hotel has been opened in the manor.
^Zarāns, Alberts (2006). Latvijas pilis un muižas. Castles and manors of Latvia (in Latvian and English). Riga. ISBN9984-785-05-X. OCLC72358861.{{cite book}}: CS1 maint: location missing publisher (link)