Norman Rupert BarrettCBEFRSA (16 May 1903 – 8 January 1979) was an Australian-born British thoracic surgeon who is widely yet mistakenly remembered for describing what became known as Barrett's oesophagus.
He trained at St. Thomas' Hospital, and graduated in 1928. He continued as resident assistant surgeon at St. Thomas' Hospital, and was elected as Fellow of the Royal College of Surgeons in 1930. He was awarded the postgraduate degree M Chir in 1931. In 1935, he became a consultant surgeon at St. Thomas', where he remained for the rest of his career.
In 1946, he wrote a paper for the first issue of Thorax on spontaneous rupture of the oesophagus (Boerhaave syndrome), in which he commented that "in the byways of surgery there can be few conditions more dramatic in their presentation and more terrible in their symptoms than spontaneous perforation of the oesophagus. No case has yet been treated successfully, and diagnosis has only been achieved in a very few before death."[2] A year later, on 7 March 1947, he performed the first successful repair of a ruptured oesophagus.[3]
In 1950, he published a paper in which he described the oesophagus as "that part of the foregut, distal to the cricopharyngeal sphincter, which is lined by squamous epithelium."[4] In this paper, Barrett suggested that the finding of an oesophagus lined with columnar epithelium (rather than the usual squamous epithelium) was due to the presence of a congenitally shortened oesophagus leading to a tubular portion of stomach being trapped in the chest. In this article Barrett credited Philip Rowland Allison for coining the term reflux oesophagitis in 1948, noting that was the 'best name for the lesion' Allison had so ably described.[4][5][6]
In contrast, Philip Rowland Allison and Alan Johnstone argued that this columnar epithelium–lined structure was oesophagus and not stomach, and suggested that ulcers in this structure be called "Barrett's ulcers".[7] Seven years after his initial article Barrett accepted this view, suggesting that it be called the "lower oesophagus lined by columnar epithelium".[8] The columnar epithelium ascending the esophagus from the stomach has subsequently become known as Barrett's oesophagus.[9]
Norman Barrett married Annabel Elizabeth "Betty" Warington Smyth on 21 April 1931. She was the sister of a school friend, and they had met six years previously. Betty had studied English and Art, and later became a novelist. They had two children, Julia and Althea. After Norman had been appointed a Consultant at St. Thomas' Hospital, the Barrett family lived at 2 Dorset Street, Marylebone, London for about 20 years. In 1954 they moved to Richmond Green.
Outside his medical interests, he was also interested in the history of medicine, drawing and painting, and was a keen sailor.
He was appointed a CBE in 1969, and retired in 1970. He died in London on 8 January 1979.
