Search Results: NOTCH4

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Notch 4
Jumat, 2025-07-18 00:39:22

protein that in humans is encoded by the NOTCH4 gene located on chromosome 6. An alternative splice variant of the NOTCH4 gene has been described, but its biological...

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Notch signaling pathway
Minggu, 2026-08-09 08:33:45

four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It...

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Schizotypal personality disorder
Selasa, 2026-08-18 13:26:07

Wassink TH, Nopoulos P, Pietila J, Crowe RR, Andreasen NC (April 2003). "NOTCH4 and the frontal lobe in schizophrenia". American Journal of Medical Genetics...

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Apurva Sarin
Rabu, 2026-01-14 11:09:50

contributions to biosciences in 2005. Source: Pub Peer: Duplicate Image: Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer...

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Nirogacestat
Minggu, 2026-08-16 09:27:10

IC50 (nM) gamma-secretase (cell-free assay) 6.2; 1.2 NICD Notch1 30.6 Notch2 27.8 Notch3 11.5 Notch4 42.6 APP intracellular domain 19.3 amyloid β-40 25.8...

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Pathway analysis
Kamis, 2026-08-06 01:22:03

(1 January 2011). "Genetic association of sequence variants near AGER/NOTCH4 and dementia". Journal of Alzheimer's Disease. 24 (3): 475–84. doi:10.3233/jad-2011-101848...

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AP-1 transcription factor
Kamis, 2026-08-13 00:15:03

(March 2007). "Glucocorticoid and growth factor synergism requirement for Notch4 chromatin domain activation". Molecular and Cellular Biology. 27 (6): 2411–22...

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MamL-1 domain
Senin, 2026-05-18 22:26:28

ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. It forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa/CBF1...

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List of human protein-coding genes 5
Selasa, 2026-08-04 21:22:45

10682 NOTCH2NLR HGNC:53925; A0A096LNW5 10683 NOTCH3 HGNC:7883; Q9UM47 10684 NOTCH4 HGNC:7884; Q99466 10685 NOTO HGNC:31839; A8MTQ0 10686 NOTUM HGNC:27106;...

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Vasculogenic mimicry
Selasa, 2026-06-23 16:27:25

found across multiple aggressive melanoma cell lines, and the inhibition of Notch4 activity in melanoma was sufficient to prevent VM formation. Another major...

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Ankyrin repeat
Minggu, 2026-05-31 03:41:33

NFKB2; NFKBIA; NFKBIB; NFKBIE; NFKBIL1; NFKBIL2; NOTCH1; NOTCH2; NOTCH3; NOTCH4; NRARP; NUDT12; OSBPL1A; OSTF1; PLA2G6; POTE14; POTE15; POTE8; PPP1R12A;...

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EGF-like domain
Senin, 2026-03-30 23:05:45

MMRN1; MMRN1; MUC4; NAGPA; NID1; NID2; NOTCH1; NOTCH2; NOTCH2NL; NOTCH3; NOTCH4; NRG1; NRG2; NRG3; NRG4; NRXN1; NRXN2; NRXN3; NTNG2; ODZ1; ODZ2; OIT3; PLAT;...

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