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the NCOR1 gene. NCOR1 is a transcriptional coregulatory protein which contains several nuclear receptor interacting domains. In addition, NCOR1 appears...
Click to read more »inactivating mutations in its negative regulators (for example, ZBTB16 and NCOR1). These androgen receptor disruptions are found in only up to 6% of biopsies...
Click to read more »DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT (NCOR2), and histone deacetylase. When ligand binds to the complex...
Click to read more »PPAR-α has been shown to interact with: AIP, EP300 HSP90AA1, NCOA1, and NCOR1. MECR Palmitoylethanolamide (PEA) Oleoylethanolamide (OEA) Anandamide (AEA)...
Click to read more »facilitating the binding of the corepressor LXX(I/H)IXXX(I/L) motif found in NCOR1 and SMRT corepressors. In analogy to SERMs, SARMs are mixed agonists/antagonists...
Click to read more »such as co-activators (e.g., COPS5, EP300, BCL3); co-repressors (e.g., NCOR1, SIN3A, TRIM24). However, there are transcription co-regulators that can...
Click to read more »a longer leucine-rich motif, LXXXIXXX(I/L), present on the corepressors NCoR1 or SMRT. In addition, some cofactors bind to ER through the terminals, the...
Click to read more »following genes belonged to the common expression groups on chromosome 17: NCOR1, GFAP, QRICH2, ANAPC11 and PER1. QRICH2 may also be an up-regulated gene...
Click to read more »factors which will affect transcription activation: BAG1, CAV3, MED12, MED24, NCOR1, NCOR2, NCOA2 RXRA, RUNX1, RUNX1T1, SNW1, STAT1, and ZBTB16. Click on genes...
Click to read more »shown to interact with: BCL6, CBX5, GATA1, HDAC3, IKZF1, MEF2A, NRIP1, NCOR1, NCOR2, YWHAQ, and ZBTB16. Histone deacetylase GRCh38: Ensembl release 89:...
Click to read more »Cardiac defect HDAC3 1 Nucleus Ubiquitous SHP, YY1, GATA1, RELA, STAT3, MEF2D NCOR1 – HDAC8 1 Nucleus/cytoplasm Ubiquitous? – EST1B – IIA HDAC4 1 Nucleus /...
Click to read more »COX8A appears to interact with NPM1, MAGEA4, EDDM3B, BATF, AMBP, CREB1, and NCOR1. GRCh38: Ensembl release 89: ENSG00000176340 – Ensembl, May 2017 GRCm38:...
Click to read more »DAXX, HSP90AA1, HNRPU, MED1, MED14, Mineralocorticoid receptor, NRIP1, NCOR1, NCOA1, NCOA2, NCOA3, POU2F1, RANBP9, RELA, SMAD3, SMARCD1, SMARCA4 STAT3...
Click to read more »observed effects. Retinoic acid receptor gamma has been shown to interact with NCOR1. Agonists Adapalene (also agonist at RARβ and weakly at RARα) CD1530 Tazarotene...
Click to read more »(ligand-dependent corepressor) Nuclear receptor CO-Repressor (NCOR) NCOR1 (NCOR1) NCOR2 (NCOR2)/SMRT (Silencing Mediator (co-repressor) for Retinoid and...
Click to read more »interact with several proteins in the SIN3 complex including SIN3B, SAP30, NCOR1, and HDAC1. Moreover, IFRD1 protein binds MyoD, MEF2C, HDAC4, HDAC3 and...
Click to read more »Q9HCD5 10324 NCOA6 HGNC:15936; Q14686 10325 NCOA7 HGNC:21081; Q8NI08 10326 NCOR1 HGNC:7672; O75376 10327 NCOR2 HGNC:7673; Q9Y618 10328 NCR1 HGNC:6731; O76036...
Click to read more »Organized Resistance. NCOR may also refer to: Nuclear receptor co-repressor 1 (NCOR1), a protein Nuclear receptor co-repressor 2 (NCOR2), a protein This disambiguation...
Click to read more »co-complex interactions. NDUFV1 appears to interact with EWSR1, CREB1, NCOR1, and VDAC1. GRCh38: Ensembl release 89: ENSG00000167792 – Ensembl, May 2017...
Click to read more »GATA1, GATA2, GPS2, GTF2I, HDAC4, HDAC5, HDAC7A, HDAC9, MAP3K7IP2, MAPK11, NCOR1, NCOR2, PPARD, PPARG, PML RBBP4, RELA, RP, RUNX2, SUV39H1, TCP1, TBL1X,...
Click to read more »be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and...
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