Raised in Ringwood, New Jersey, Hoffmann attended Ramapo High School.[2] After winning two consecutive New Jersey state championships, Hoffmann relocated to the International Junior Golf Academy in Hilton Head, South Carolina to take advantage of the warm-weather and training opportunities.[3] Hoffmann's girlfriend is Chelsea Colvard, they met while she was living in Miami through mutual Oklahoma State University friends.
After playing in the 2010 U.S. Open, Hoffmann decide to leave college early in order to turn professional. He qualified for his first professional major at the 2012 U.S. Open, finishing in a tie for 29th.
Hoffmann played on the Web.com Tour in 2012, starting the season with no status and getting by on sponsor exemptions and Monday qualifiers. He played in 13 events and finished 19th on the money list, which earned him a promotion to the PGA Tour. In 2017, Hoffmann finished T2 at The Honda Classic, which is his highest finish in his career.
In December 2017, Hoffmann announced that he had been diagnosed with facioscapulohumeral muscular dystrophy (FSHD).[6] In the days afterwards, Hoffmann was inundated and overwhelmed by messages of support from his fellow pros and members of the public.[7] In April 2022, Hoffman returned after undergoing treatment, and competed on the PGA Tour for the first time in three years.[8]
^Punty, Brendan (June 28, 2008). "Hoffmann swinging for the pros". The Star-Ledger. Retrieved October 30, 2013. Morgan Hoffmann, then a 16-year-old from Ramapo High School in Franklin Lakes, wowed McGraw with his power, his ball-striking ability and first and foremost his desire to win. ... It was the same desire that he displayed in winning back-to-back New Jersey high school championships. ... So he left his home in Wyckoff to pursue his dream – attending Hank Haney's International Junior Golf Academy in Hilton Head, S.C., in early 2007 and working with Gary Gilchrist in Orlando this past winter.
^Prunty, Brendan (June 25, 2008). "Somerville's Foley outduels Hoffmann to take Ike title". The Star-Ledger. Retrieved December 17, 2013. But Hoffmann did stay close and was one shot back as they came to the par-3 14th hole. However, an errant tee shot forced the Saddle Brook resident to scramble and make par, while Foley made another birdie.