Milo post office was established in 1923; Cora E. Buker was the first postmaster.[2] It was named for Milo, Maine, the hometown of Amos O. Buker, who was the husband of Cora.[2] Originally the post office at this locale was named "Perdue", named after John Perdue, Sr., who was also its first postmaster.[2] It was originally at the confluence of the South Umpqua River and Elk Creek—which today is the location of Tiller—and the office was first called "Elk Creek".[2] Elk Creek post office was founded in 1877.[2] Perdue took over as postmaster of the Elk Creek post office on June 11, 1884 and on August 22, the name was changed to Perdue.[2] At the same time the office was moved to the current location of Milo.[2] The office was closed in 1920 when no one could be found to replace then-postmaster Amos Buker, who was fired after he had acted against postal regulations by working as a United States Census enumerator.[2] Today Milo has a Days Creek mailing address.[3][4]