The area has become a major business center in the state, for its growing production of paper products, textile, medical supplies and steel. It is also a center for farming and medical care. The area is also involved in attractions and tourism, featuring shopping, fishing and amusement.
As of the 2020 census the Midlands population was 1,019,439.
Counties
The Midlands area of South Carolina includes at least these eight counties:
This region is largely coextensive with the Columbia metropolitan area (which includes Newberry and Orangeburg counties) but .
The middle portion of Orangeburg County is located in the Midlands, while the western part is located in the Central Savannah River Area and the eastern part is considered to be located in the Lowcountry. Other than being designated to the Augusta, GA market, Aiken County is also frequently listed as part of the Central Savannah River Area.