Nosseck's American films typed him as a director of sensationalist subjects, usually juvenile-vagrancy melodramas. His most famous "exploitation" film is Dillinger (1945), a gangster picture chronicling the rise and fall of John Dillinger. The film starred Lawrence Tierney, with whom Nosseck reunited for two crime thrillers in later years. In a surprising turnabout, Nosseck directed two wholesome animal adventures in 1946 and 1947.
After his American assignments, he returned to work in the German and Austrian film industries. Nosseck married three times: to Austrian actress Olly Gebauer, to German actress Ilse Steppat, and to the writer and aviator Genevieve Haugen.