Azem's first dubbing role was that of Tildy in the Disney cartoon Danny le petit mouton noir (So Dear to My Heart), when she was 7 years old.[2]
In 2001 she dubbed the voice of actress Emma Watson in the role of Hermione Granger in the film Harry Potter and the Philosopher's Stone, going on to become the official French voice in all the Harry Potter films until 2015 when she decided her voice had become too deep to portray the British actress.[1] However, in 2021 she reprised her role and dubbed Watson's words in the documentary Harry Potter 20th Anniversary: Return to Hogwarts[4] and in August 2022 dubbed Watson's voice in an advertisement for Paradoxe perfume by Prada.[5]
For six seasons, Azem played Dunk, one of the main characters in the Disney Channel series Trop la Classe. She is also known for her role as Officer Sara Casanova in the TF1 series Section de recherches.[6]
Azem, whose paternal family are Palestinian citizens of Israel, has spoken about what she called "the racism, harassment, and apartheid Palestinians face", even if they hold Israeli passports. In 2024, she claimed having received death and rape threats for defending the Palestinian cause.[12]