He currently conducts research in the broad fields on Machine Learning, Computer Vision and Computational Advertising. In 2013, he started and popularized a new area in machine learning called Extreme Classification (also known as Extreme Multi-label Classification).[1][2][3] Extreme Classification focuses on Multi-Label Classification at the scale of millions of labels and helps rethink traditional problems of ranking and recommendation.[4] Extreme Classification is thriving in both academia and industry with product integrations in Bing and Amazon.[4][1] Manik Varma along with his colleagues at MSR India also proposed another paradigm in machine learning called Edge Machine Learning[5] to enable machine learning predictions on tiny IoT devices with as little as 2 KB of RAM assisting in low-energy, low-latency and privacy preserving applications of AI. In the past, he worked on statistical approaches to texture classification, object detection, multiple kernel learning and ranking.