MDPCP

Methylenedioxyphencyclidine (3,4-MD-PCP, MDPCP) is a recreational designer drug with dissociative effects. It is an arylcyclohexylamine derivative, with similar

MDPCP
MDPCP
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC18H25NO2
Molar mass287.403 g·mol−1
3D model (JSmol)
  • C1CCC(CC1)(N1CCCCC1)c1ccc2c(c1)OCO2
  • InChI=1S/C18H25NO2/c1-3-9-18(10-4-1,19-11-5-2-6-12-19)15-7-8-16-17(13-15)21-14-20-16/h7-8,13H,1-6,9-12,14H2
  • Key:ANUGFLCSICVCSB-UHFFFAOYSA-N

Methylenedioxyphencyclidine (3,4-MD-PCP, MDPCP) is a recreational designer drug with dissociative effects. It is an arylcyclohexylamine derivative, with similar effects to related drugs such as 3-MeO-PCP and 4-MeO-PCP.[1][2]

Chemical properties

MDPCP has the molecular formula C18H25NO2 and a molar mass of 287.403 g·mol−1. Its structural characteristics include a methylenedioxy functional group attached to the phenyl ring, a hallmark of several psychoactive substances within this category.

Pharmacology and effects

As a dissociative drug, MDPCP exerts its effects primarily through antagonism of the NMDA receptor, resulting in altered sensory perceptions and dissociative states. The drug's subjective effects are reported to be similar to those of related arylcyclohexylamine derivatives. It has been reported to have an affinity of 63 nM for NMDARs determined in rat forebrains and was reasonably selective over other receptors tested including monoamine transporters and opioid receptors.[3][2]

Given its status as a novel psychoactive substance, MDPCP may be subject to varying degrees of legal control across different jurisdictions, often falling under generic legislation targeting arylcyclohexylamine derivatives or dissociative substances.

See also

References

  1. ^ Wallach JV (2014). Structure activity relationship (SAR) studies of arylcycloalkylamines as N-methyl-D-aspartate receptor antagonists (Ph.D. thesis). University of the Sciences in Philadelphia. 3690548.
  2. ^ a b Wallach J, Brandt SD (2018). "Phencyclidine-Based New Psychoactive Substances". New Psychoactive Substances. Handbook of Experimental Pharmacology. Vol. 252. pp. 261–303. doi:10.1007/164_2018_124. ISBN 978-3-030-10560-0. PMID 30105474.
  3. ^ Wallach JV (2014). Structure activity relationship (SAR) studies of arylcycloalkylamines as N-methyl-D-aspartate receptor antagonists (Ph.D. thesis). University of the Sciences in Philadelphia. 3690548.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.