Knox Ramsey played college football at the College of William & Mary where he was selected for three consecutive years to Virginia's all-state teams and the Southern Conference teams. He also was named to the all-time state of Virginia team and the all-time William & Mary football team.[1] Ramsey received second-team All-American honors in 1947 when he was selected by the Associated Press. He played in the 1948 College All-Star Game against the NFL Champions Chicago Cardinals where he faced his brother Buster Ramsey. Ramsey was drafted in the fifth round of the 1948 NFL draft (32nd pick overall) by the Chicago Bears and in the ninth round (37th pick overall) of the 1948 AAFC Draft by the Los Angeles Dons. Following his professional football career Ramsey was inducted into the William & Mary Hall of Fame and the Blount County (TN) Sports Hall of Fame.