The Pangaio mountains, reaching 1,957 m are situated in the west. The neighbouring regional units are Serres to the west, Drama to the north and Xanthi to the east. The river Nestos flows along the eastern border. Arable lands are located along the coastline, in the north and in the east.
The regional unit has a predominantly Mediterranean climate.
Administration
The regional unit Kavala is subdivided into three municipalities. These are (number as in the map in the infobox):[2]
As a part of the 2011 Kallikratis government reform, the former Kavala Prefecture (Greek: Νομός Καβάλας) was transformed into a regional unit within the East Macedonia and Thrace region. The prefecture also included the island of Thasos, which became a separate regional unit. At the same time, the municipalities were reorganised, according to the table below.[2]