Burton was born in Geneva, Switzerland, the daughter of Welsh parents, producer Sybil Burton (née Williams) and actor Richard Burton.[5] She was thus the stepdaughter of Elizabeth Taylor and of Sybil's second husband Jordan Christopher, both actors. Burton earned a bachelor's degree in Russian Studies and European History from Brown University in 1979, where she was on the board of Production Workshop, one of the university's student theater groups, and a master's degree from Yale School of Drama in 1982. Brown awarded Burton an honorary doctorate in 2007.[6][7]
Burton has been perhaps most prolific in her work on television. She made many television appearances in the late 1980s and 1990s on such episodic shows as Spenser: For Hire, All My Children, and Brooklyn Bridge. About playing the mother, in her late thirties, of David Schwimmer's character in the short-lived 1994 FOX sitcom, Monty, she said, "you don't really start playing moms in Hollywood until you're in your 40s, and usually the kids are almost your age! When I played Schwimmer's mother, I was 37 and he was, I think, 28. . . that happens a lot in TV and film; you really do end up being close in age to your child, which is nonsensical."[18] In 1996, Burton won a Daytime Emmy award for her performance as a mother dying of breast cancer in the ABC Afterschool Special, 'Notes for my Daughter'. More recently, she made guest appearances as recurring characters on Law & Order, The Practice, The West Wing, Judging Amy and Medium. She also appeared on the HBOminiseriesEmpire Falls.
Some of her recurring television roles have involved subplots concerning Alzheimer's disease. On FX network's Rescue Me, she played the role of Rose, a friend and possible romantic interest to Chief Jerry Reilly. Reilly, whose wife is in a facility suffering from Alzheimer's, hires Rose, a caregiver for her husband who was also a victim, to provide assistance and emotional support. Burton's most visible and well-known role to date is the mysterious and difficult mother of Dr. Meredith Grey (Ellen Pompeo), the titular character on ABC's medical dramaGrey's Anatomy. Burton plays Dr. Ellis Grey, the former trailblazing surgeon, and a two-time winner of the fictionalized, prestigious Harper Avery Award. Her character's battle and death of Alzheimer's is central to Meredith's story in all seasons of the series, as Meredith fears both getting the disease and resembling her mother as she ages. The character is also revealed to be the birth mother of Meredith's half-sister, Dr. Maggie Pierce (Kelly McCreary) through her love affair with Dr. Richard Webber (James Pickens, Jr.).
Like Schwimmer's character in Monty, Burton and Pompeo (who portrays Meredith) also have a small age gap, with Pompeo being 12 years her junior. In-universe, Meredith (born 1978) is 25 years younger than Ellis (born 1953), with Pompeo aged down 11 years and Burton aged up 4 years. (Though the character's exact ages were not determined until a retcon was established in season 11). In 2008, the New York City Chapter of the Alzheimer's Association singled her out for her compelling performances in both shows.[19] In 2006 and 2007, Burton received Emmy nominations for her Grey's Anatomy role.[20] Burton's character dies in the third season episode "Some Kind of Miracle", which aired in 2007; she returned to the role five years later, in the season 8 alternate reality episode. It depicts a version of her life where Richard did not leave her and she did not have Alzheimer's. Burton's character is central to the eleventh season, as Meredith's marital struggles begin to parallel her own mother's struggles, something she feared. She reprised her role in flashbacks for the eleventh season, showing Ellis briefly before her Alzheimer's diagnosis. In season 14's landmark 300th episode, Burton's Ellis is shown as a dream-sequence figure, clapping for Meredith, who has also now won a Harper Avery award. She re-appears twice as a dream sequence figure in the fifteenth season. Burton will return to the role in the eighteenth season, beginning with its season premiere.
In 2011, Burton appeared as Marie Kessler, a veteran monster hunter, and the aunt of Nick Burkhardt in the opening episodes of the NBC supernatural drama Grimm. Since 2012, she plays the recurring role of Vice President Sally Langston in the ABC hit show Scandal, for which she again received an Emmy nomination.[21][20] In 2015, it was reported that Burton was cast in a leading role in the U.S. remake of the French-language film Martyrs, which opened theatrically in January 2016.[22][23] In March 2017, she reprised her role as Aunt Marie Kessler in the series finale of Grimm.
^Findlater, Richard (December 28, 1959). "Life with the Swiss family Burton". Evening Standard (London). p. 5. Retrieved July 30, 2022 – via Newspapers.com.