While studying child psychology, Kanemaru worked part-time at the Far East Network in Yokota Air Base, and at a department store as a studio DJ in Shinjuku.[5] He joined in the dubbing session for Urusei Yatsura.[6] He later took part in several of Fuji TV's Saturday evening shows such as High School! Kimengumi, Tsuide ni Tonchinkan, and Meimon! Dai San Yakyūbu. At the time, he was employed by Beniya 25-Ji and Dojinsha Production. He got his first lead role in 1991's Future GPX Cyber Formula, where he played Hayato Kazami. He found out about it the day before the recording, when he heard an answering machine on his trip, and rushed home to read the script on the day of the recording.[6] When he appeared in Cyber Formula, he was also working as an English tutor, and one of his students' parents leaked information about him, causing a huge commotion in the adjacent shopping district as anime fans rushed to the place where he was teaching.
During the dubbing of an American television sitcom Growing Pains, a SEGA official who came to look for the role of Sonic heard Kanemaru's performance in the waiting room and cast him for the role starting from Sonic Adventure.[6] This established a role for Sonic, who could freely switch between English and Japanese, and also led to Kanemaru's role. His performance in the Sonic series also led to offers from Disney to record children's programs. For the live-action film adaptation for the Sonic series, Kanemaru was replaced by Taishi Nakagawa. At the time the film was released, Kanemaru took to Twitter to express his thoughts and support the crew for the film.
In an interview with Animate Times in 2016, Kanemaru recalled that Cyber Formula helped him get used to singing, as the series had monthly album releases at the time.[6] He was the first in the voice acting industry to be allowed to cover "Ue o Muite Arukō" and recorded it with an a cappella chorus. On his 1993 album Inspired Colors, he also wrote and composed the song "12-Gatsu no Fairy Tale", as well as English covers of "Video Killed the Radio Star" and Kazumasa Oda's "Love Story wa Totsuzen ni" under the title "suddenly" (using the lyrics from Rita Coolidge's version). He has also tried his hand at standard jazz and has performed several live shows with several fellow voice actors, and his jazz numbers mixed with English and Japanese lyrics written himself are well received by all ages.