Mayans is considered a close ally of longtime Formosa governor Gildo Insfrán.[3] Mayans has been described as a "fanatic anti-abortion lobbyist" despite being part of the progressive-leaning Peronist movement. His conservative views have, at times, put him at odds with Peronist presidents Cristina Fernández de Kirchner and Alberto Fernández.[4]
Mayans was elected to the Argentine Senate in 2001, and has been re-elected four times: in 2005, 2011, 2017, and 2023.[5] After having served as vice-president of the Front for Victory bloc for 17 years, he was elected as president of the Frente de Todos bloc upon the coalition's establishment in 2019. Prior to being elected to the Senate, he was a member of the Chamber of Deputies of Formosa from 1987 to 2001.[6]
^"Escrutinio Definitivo"(PDF). mininterior.gov.ar (in Spanish). Subsecretaría de Asuntos Institucionales. Archived from the original(PDF) on 28 December 2018. Retrieved 4 February 2023.
^"Escrutinio Definitivo"(PDF). mininterior.gov.ar (in Spanish). Subsecretaría de Asuntos Institucionales. Archived from the original(PDF) on 24 October 2018. Retrieved 4 February 2023.
^"Escrutinio Definitivo"(PDF). mininterior.gov.ar (in Spanish). Subsecretaría de Asuntos Institucionales. Archived from the original(PDF) on 19 March 2018. Retrieved 4 February 2023.
^"Escrutinio Definitivo"(PDF). mininterior.gov.ar (in Spanish). Subsecretaría de Asuntos Institucionales. Archived from the original(PDF) on 24 March 2016. Retrieved 4 February 2023.
^"Elecciones 2001". argentina.gob.ar (in Spanish). Dirección Nacional Electoral. 7 February 2019. Retrieved 4 February 2023.
^"Elecciones 2005". argentina.gob.ar (in Spanish). Dirección Nacional Electoral. 8 February 2019. Retrieved 4 February 2023.
^"Elecciones 2011". argentina.gob.ar (in Spanish). Dirección Nacional Electoral. 29 August 2017. Retrieved 4 February 2023.
^"Elecciones 2017". argentina.gob.ar (in Spanish). Dirección Nacional Electoral. 27 September 2017. Retrieved 4 February 2023.