Saylor was elected as a Republican to the 81st Congress, by special election, September 13, 1949, to fill the vacancy caused by the death of Robert L. Coffey. He was reelected to the twelve succeeding Congresses and served until his death in Houston, Texas. During his time in Congress he became dedicated to a number of environmental causes, including the Wilderness Act of 1964,[1] the Ozark National Scenic Riverways Act, National Wild and Scenic Rivers Act and in opposition to the Kinzua Dam Project.[2] He was dubbed "St. John" by environmental advocates for his dogged work on environmental issues.
In 1970 the Izaak Walton League of America bestowed its highest honor, the Founders' Award, to Saylor "for two decades of unprecedented leadership in the Congress of the United States for sound resource management, the preservation of natural scenic and cultural values, the maintenance of a quality environment, and the unalienable right of citizens to be involved in resources and environmental decisions."[3]