Burrow's last coaching position was as defensive coordinator for Ohio University from 2005 until his retirement after the 2018 season. At the time of his retirement, he had been one of the longest-tenured coordinators in Division I football. He was associate head coach from 2017 until his retirement. For his efforts, Burrow was named Scout.com's 2009MAC Defensive Coordinator of the Year.
Burrow previously coached at various positions for, respectively, Washington State, Iowa State, Ames High School, Nebraska, and North Dakota State.[3] He timed his retirement from coaching to coincide with the final college football season of his son Joe Burrow, who played at LSU in 2019. The elder Burrow publicly acknowledged that his wish to attend all of his son's 2019 games played a role in his retirement decision.[4]