INSIG1

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Insulin-induced gene 1 protein

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Insulin-induced gene 1 protein

Sabtu, 2025-07-19 13:09:31

Insulin induced gene 1, also known as INSIG1, is a protein which in humans is encoded by the INSIG1 gene. INSIG1 is short for insulin-induced gene 1; it...

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Adipocyte

Minggu, 2026-08-16 08:31:32

is retained in the ER membrane by INSIG1 (insulin-induced gene 1 protein). When sterol levels are depleted, INSIG1 releases SCAP and the SREBF1-SCAP complex...

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INSIG2

Jumat, 2025-10-17 20:24:52

this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that...

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HMG-CoA reductase

Jumat, 2026-08-14 04:55:22

nSREBP transcription factor is short-lived. When cholesterol levels rise, INSIG1 and INSIG2 retain the SCAP-SREBP complex in the ER membrane by preventing...

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Zhimin Lu

Selasa, 2026-04-14 17:08:52

Zhimin (April 16, 2020). "The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis". Nature. 580 (7804): 530–535. Bibcode:2020Natur.580....

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Sterol regulatory element–binding protein 2

Rabu, 2025-11-26 08:38:59

higher risk of knee osteoarthritis. SREBF2 has been shown to interact with INSIG1 and the CREB-binding protein. Sterol regulatory element-binding protein...

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List of human protein-coding genes 4

Kamis, 2026-06-18 06:08:52

HGNC:6080; O15357 7697 INS HGNC:6081; P01308 7698 INSC HGNC:33116; Q1MX18 7699 INSIG1 HGNC:6083; O15503 7700 INSIG2 HGNC:20452; Q9Y5U4 7701 INSL3 HGNC:6086; P51460...

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