HABP4

HABP4
Identifiers
Aliases	HABP4, IHABP-4, IKi-1/57, SERBP1L, hyaluronan binding protein 4
External IDs	OMIM: 617369; MGI: 1891713; GeneCards: HABP4
Gene location (Human)
Chr.	Chromosome 9 (human)
End	96,491,336 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	64,334,351 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; nucleus accumbens; ; olfactory bulb; ; beta cell; ; putamen; ; right frontal lobe; ; caudate nucleus; ; cingulate gyrus; ; amygdala; ; anterior cingulate cortex;
	Top expressed in
	superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; central gray substance of midbrain; ; seminiferous tubule; ; medial vestibular nucleus; ; dorsal tegmental nucleus; ; neural layer of retina; ; right kidney; ; deep cerebellar nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; SUMO binding;
Cellular component	extracellular region; sarcomere; nucleus; cytoplasm; nucleolus; Cajal body; sarcoplasm; nuclear body; nuclear speck; gemini of coiled bodies; cytosol; cytoplasmic stress granule;
Biological process	negative regulation of DNA binding; cellular response to mechanical stimulus; platelet degranulation; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of RNA splicing; positive regulation of translational initiation; mRNA processing; regulation of translation; RNA splicing; PML body organization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	22927
	56541
	ENSG00000130956
	ENSMUSG00000021476
	Q5JVS0
	Q9JKS5
	NM_014282
	NM_019986
	NP_055097
	NP_064370
	Wikidata
View/Edit Human	View/Edit Mouse

Intracellular hyaluronan-binding protein 4 is a protein that in humans is encoded by the HABP4 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130956 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021476 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kobarg J, Schnittger S, Fonatsch C, Lemke H, Bowen MA, Buck F, Hansen HP (May 1998). "Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen". Exp Clin Immunogenet. 14 (4): 273–80. PMID 9523163.
^ Huang L, Grammatikakis N, Yoneda M, Banerjee SD, Toole BP (Nov 2000). "Molecular characterization of a novel intracellular hyaluronan-binding protein". J Biol Chem. 275 (38): 29829–39. doi:10.1074/jbc.M002737200. PMID 10887182.
^ "Entrez Gene: HABP4 hyaluronan binding protein 4".

Rohde D, Hansen H, Hafner M, et al. (1992). "Cellular localizations and processing of the two molecular forms of the Hodgkin-associated Ki-1 (CD30) antigen. The protein kinase Ki-1/57 occurs in the nucleus". Am. J. Pathol. 140 (2): 473–82. PMC 1886443. PMID 1310832.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lemos TA, Passos DO, Nery FC, Kobarg J (2003). "Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3". FEBS Lett. 533 (1–3): 14–20. doi:10.1016/S0014-5793(02)03737-7. PMID 12505151. S2CID 41197943.
Nery FC, Passos DO, Garcia VS, Kobarg J (2004). "Ki-1/57 interacts with RACK1 and is a substrate for the phosphorylation by phorbol 12-myristate 13-acetate-activated protein kinase C". J. Biol. Chem. 279 (12): 11444–55. doi:10.1074/jbc.M306672200. PMID 14699138.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kobarg CB, Kobarg J, Crosara-Alberto DP, et al. (2005). "MEF2C DNA-binding activity is inhibited through its interaction with the regulatory protein Ki-1/57". FEBS Lett. 579 (12): 2615–22. doi:10.1016/j.febslet.2005.03.078. PMID 15862299. S2CID 26654365.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Nery FC, Rui E, Kuniyoshi TM, Kobarg J (2006). "Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins". Biochem. Biophys. Res. Commun. 341 (3): 847–55. doi:10.1016/j.bbrc.2006.01.036. PMID 16455055.
Passos DO, Bressan GC, Nery FC, Kobarg J (2006). "Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation". FEBS J. 273 (17): 3946–61. doi:10.1111/j.1742-4658.2006.05399.x. PMID 16879614. S2CID 25895297.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000130956 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021476 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9523163-5] Kobarg J, Schnittger S, Fonatsch C, Lemke H, Bowen MA, Buck F, Hansen HP (May 1998). "Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen". Exp Clin Immunogenet. 14 (4): 273–80. PMID 9523163.

[pmid10887182-6] Huang L, Grammatikakis N, Yoneda M, Banerjee SD, Toole BP (Nov 2000). "Molecular characterization of a novel intracellular hyaluronan-binding protein". J Biol Chem. 275 (38): 29829–39. doi:10.1074/jbc.M002737200. PMID 10887182.

[entrez-7] "Entrez Gene: HABP4 hyaluronan binding protein 4".

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HABP4

References

Further reading

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