Genderblind

Genderblind, also known as CG6070, is a gene that was discovered in Drosophila melanogaster by University of Illinois at Chicago researcher David Featherstone.&

Genderblind
For other uses, see Gender-blind.
Genderblind
Identifiers
OrganismDrosophila melanogaster
Symbolgb
UniProtQ9VB75
Search for
StructuresSwiss-model
DomainsInterPro

Genderblind, also known as CG6070, is a gene that was discovered in Drosophila melanogaster by University of Illinois at Chicago researcher David Featherstone.[1] The gene encodes a member of the cystine/glutamate transporter family of proteins.

Genderblind protein is expressed in glial cells where it secretes the neurotransmitter glutamate and regulates the organization of glutamate receptors.[2]

A mutation in Genderblind alters the sexual behavior of Drosophila, turning the flies bisexual.[1] Drosophila given drugs to alter synapse strength, independent of the Genderblind mutation, allowed researchers to "turn fly homosexuality on and off, within hours".[1] The researchers believe this effect is due to the flies' altered response to pheromones.

References

  1. ^ a b c "Homosexuality Turned On and Off in Fruit Flies", LiveScience, 9 December 2007, accessed 10 December 2007
  2. ^ Augustin H, Grosjean Y, Chen K, Sheng Q, Featherstone DE (2007). "Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo". J. Neurosci. 27 (1): 111–23. doi:10.1523/JNEUROSCI.4770-06.2007. PMC 2193629. PMID 17202478.


Stub icon

This gene article is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.