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Fibroma of tendon sheath
Fibroma of tendon sheath
	Photomicrograph of a fibroma of tendon sheath of the finger
Specialty	Plastic surgery

Fibroma of tendon sheath is a benign tumor that presents as a small subcutaneous nodule that slowly increases in size.^[1] This is a notably uncommon condition. According to case report literature, the tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.”^[2] A common microscopic finding is the presence of elongated, slit-like blood vessels.^[2] The lesions nearly always arise in the distal portions of the extremities.^[2] They often occur on the fingers, hands, toes, or feet. Although they are benign, they may recur after surgical excision in up to 40% of people.^[1]

Although they may be regarded as a tumor of the skin, the lesions arise from tendons and aponeuroses in superficial sites, and are therefore properly classified in the category of soft-tissue tumor.^[2] The World Health Organization in 2020 reclassified these tumors as a specific, benign tumor type in a broad category of soft tissue neoplasms termed fibroblastic and myofibroblastic tumors.^[3]

The biological nature of fibroma of tendon sheath is not known, but the category appears to comprise a number of different pathological processes.^[2] It is considered that about one-third of the lesions in this category may be acral variants of the entity nodular fasciitis.^[2]

References

^ ^a ^b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1820, 1821. ISBN 978-1-4160-2999-1.
^ ^a ^b ^c ^d ^e ^f Pulitzer DR, Martin PC, Reed RJ (June 1989). "Fibroma of Tendon Sheath (A Clinicopathologic Study of 32 Cases)". American Journal of Surgical Pathology. 13 (6): 472–479. doi:10.1097/00000478-198906000-00003. PMID 2729499. S2CID 43340253.
^ Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". Pathologica. 113 (2): 70–84. doi:10.32074/1591-951X-213. PMC 8167394. PMID 33179614.