ECT2L

345930

ECT2L
ECT2L
Identifiers
AliasesECT2L, ARHGEF32, C6orf91, FBXO49, LFDH, dJ509I19.2, dJ509I19.3, dJ509I19.5, epithelial cell transforming 2 like
External IDsMGI: 3641723; GeneCards: ECT2L
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

345930

100045792

Ensembl

ENSG00000203734

ENSMUSG00000071392

UniProt

Q008S8

n/a

RefSeq (mRNA)

NM_001077706
NM_001195037

NM_001195036
NM_001370991

RefSeq (protein)

NP_001071174
NP_001181966

n/a

Location (UCSC)Chr 6: 138.8 – 138.9 MbChr 10: 18 – 18.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Epithelial cell transforming sequence 2 oncogene-like is a protein that in humans is encoded by the ECT2L gene.[5]

Clinical relevance

Recurrent mutations of this gene have been associated to cases of acute lymphoblastic leukaemia.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000203734 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071392 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Epithelial cell transforming sequence 2 oncogene-like". Retrieved 2012-02-19.
  6. ^ Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG (2012). "The genetic basis of early T-cell precursor acute lymphoblastic leukaemia". Nature. 481 (7380): 157–163. Bibcode:2012Natur.481..157Z. doi:10.1038/nature10725. PMC 3267575. PMID 22237106.
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