Doi's sign

Doi's sign
Differential diagnosis	Eaton-Lambert syndrome

Doi's sign is a clinical sign in which absent deep tendon reflexes can be elicited after a short period of maximal muscle contraction. This occurs in patients with Eaton-Lambert syndrome, but is not seen in patients with neuropathy.^[1]

The sign is named after Hitoka Doi, M.D., who described it in 1978.^[2]

References

1. Jane M. Orient, Joseph D. Sapira. Sapira's art & science of bedside diagnosis, 3rd edition, page 610. Google books
2. Doi, H; Murai Y; Kuroiwa Y (1978). "Deep tendon reflex in Eaton-Lambert syndrome". Folia Psychiatr Neurol Jpn. 32 (1): 109–13. doi:10.1111/j.1440-1819.1978.tb02784.x. PMID 207629. S2CID 7380547.