Deoxyinosine monophosphate

Deoxyinosine monophosphate

Names
IUPAC name 2’-Deoxy-5’-inosinic acid
Other names dIMP
Identifiers
CAS Number	3393-18-8^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:28806
ChemSpider	82650
ECHA InfoCard	100.020.216
PubChem CID	91531
UNII	T2SLS3P7A9^Y
CompTox Dashboard (EPA)	DTXSID60937065
InChI InChI=1S/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1 Key: PHNGFPPXDJJADG-RRKCRQDMSA-N InChI=1/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1 Key: PHNGFPPXDJJADG-RRKCRQDMBF
SMILES O=C3/N=C\Nc1c3ncn1[C@@H]2O[C@@H]([C@@H](O)C2)COP(=O)(O)O
Properties
Chemical formula	C10H13N4O7P
Molar mass	332.209 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Deoxyinosine monophosphate (dIMP) is a nucleoside monophosphate and a derivative of inosinic acid. It can be formed by the deamination of the purine base in deoxyadenosine monophosphate (dAMP). The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in S. cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyses dITP, resulting in the release of pyrophosphate and dIMP.^[1]

See also

• Xanthosine
• Xanthosine monophosphate

References

1. Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports. 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.