Driscoll was playing baseball professionally for local teams in Lowell and Nashua, New Hampshire by the age of 15. In November, 1882, he married 18-year old Mary Driscoll of Westford, Massachusetts. Soon afterwards he moved to Westford, most likely in the village of Graniteville, as the Casey family members were employed in the local granite quarries and mills. After the death of his father-in-law, Driscoll supported the Casey family with his baseball salary. In vital records of the early 1880s, he alternately listed his occupation as 'ball player' or 'machinist'. Denny Driscoll had two children with Mary, John William, born September 17, 1883, and Lizzie, born April 21, 1885.[3]
Driscoll died in his hometown of Lowell, Massachusetts at the age of 30 of consumption (tuberculosis).[4] He is interred at St. Patrick Cemetery.[1]