Delayed gadolinium-enhanced magnetic resonance imaging of cartilage
Medical diagnostic method
Delayed gadolinium-enhanced magnetic resonance imaging of cartilage
dGEMRIC T1 Map of knee cartilage
Purpose
measures relative proteoglycan content of articular cartilage
Delayed gadolinium-enhanced magnetic resonance imaging of cartilage or dGEMRIC measures the fixed-charge density and relative proteoglycan content of articular cartilage using the spin-lattice relaxation time or T1 relaxation time.[1] Current research is investigating the clinical application of dGEMRIC as a quantitative tool for monitoring cartilage function in diseased or repair cartilage.[2]
References
^Bashir, A; Gray, ML; Boutin, RD; Burstein, D (Nov 1997). "Glycosaminoglycan in articular cartilage: in vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging". Radiology. 205 (2): 551–8. doi:10.1148/radiology.205.2.9356644. PMID9356644.