To date, Arsene's professional career has been almost solely in the American Hockey League, where he has played twelve seasons. He spent six of those seasons (from 2003–04 to 2008–09) with the Hershey Bears, winning the league's championship Calder Cup twice in that tenure, and earning the fond nickname "Mayor of Chocolatetown."
Following his second Calder Cup, Arsene chose to sign the two-way contract with the Edmonton Oilers in the hope of earning some playing time in the NHL on July 16, 2009.[1] That hope was realized when he was called up for a two-game stint in late 2009.[2] He spent the majority of the 2009–10 season as the captain of the Springfield Falcons, however, he was again later recalled on an emergency basis on March 22, 2010, finishing out the season with Edmonton.
Arsene signed a one-year contract with the Phoenix Coyotes on July 6, 2011.[4] He spent the entirety of the 2011–12 season, with AHL affiliate, the Portland Pirates.
On August 9, 2012, Arsene agreed to a one-year American League contract with the St. John's IceCaps.[5]
In his final professional season, Arsene returned home, signing a one-year contract with the Abbotsford Heat for the 2013–14 campaign. Arsene posted 7 points in 42 games before announcing his retirement upon the Heat's first-round exit in the playoffs on May 7, 2014.[6]