Copper gluconate

Copper gluconate

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a601072
Routes of administration	Oral
ATC code	V03AB20 (WHO)
Identifiers
IUPAC name Copper(II) gluconate
CAS Number	527-09-3^Y
PubChem CID	10692
ChemSpider	10242^N
UNII	RV823G6G67
CompTox Dashboard (EPA)	DTXSID4035960
ECHA InfoCard	100.007.645
Chemical and physical data
Formula	C12H22CuO14
Molar mass	453.840 g·mol^−1
3D model (JSmol)	Interactive image
Melting point	156 °C (313 °F)
Solubility in water	30 mg/mL (20 °C)
SMILES C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cu+2]
InChI InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1^N Key:OCUCCJIRFHNWBP-IYEMJOQQSA-L^N
^NY (what is this?)  (verify)

Copper gluconate is the copper salt of D-gluconic acid. It is an odorless light blue or blue-green crystal or powder which is easily soluble in water and insoluble in ethanol.^[1][2]

Uses

• Dietary supplement to treat copper deficiency.
• Ingredient of Retsyn, which was an ingredient of Certs breath mints.
• Fertilizer deficiency corrector to treat lacks of this nutrient.^[3]

Side effects

The U.S. Institute of Medicine (IOM) sets tolerable upper intake levels (ULs) for vitamins and minerals when evidence is sufficient. In the case of copper the adult UL is set at 10 mg/day.^[4]

Copper gluconate is sold as a dietary supplement to provide copper. The typical dose is 2.0 mg copper per day. This is one-fifth what the IOM considers a safe upper limit. Long-term intake at amounts higher than the UL may cause liver damage.^[4]

References

1. "产品列表-葡萄糖酸铜" [Product list - copper gluconate]. Liaoyang Tengyuan Food Additives Factory. Archived from the original on April 2, 2015. Retrieved March 29, 2013. (in Chinese)
2. "Copper Gluconate". ChemicalLand21. Retrieved March 29, 2013.
3. Sawyer DT (1964). "Metal-Gluconate Complexes". Chemical Reviews. 64 (6): 633–643. doi:10.1021/cr60232a003.
4. Food and Nutrition Board, Institute of Medicine (2001). "Chapter 9: Copper". DRI: dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc : a report of the Panel on Micronutrients ... and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Washington, D.C.: National Academy Press. pp. 224–257. ISBN 978-0-309-07290-8.

External links

• Copper gluconate monograph at Drugs.com