Cilostamide

Cilostamide

Names
Preferred IUPAC name N-Cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide
Identifiers
CAS Number	68550-75-4^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL34431
ChemSpider	2651
IUPHAR/BPS	5167
PubChem CID	2753
UNII	45S5605Q18^Y
CompTox Dashboard (EPA)	DTXSID3045140
InChI InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23) Key: UIAYVIIHMORPSJ-UHFFFAOYSA-N
SMILES CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
Properties
Chemical formula	C20H26N2O3
Molar mass	342.439 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Cilostamide is a PDE3 inhibitor.^[1]

References

1. De Jonge, HR; Tilly, BC; Hogema, BM; Pfau, DJ; Kelley, CA; Kelley, MH; Melita, AM; Morris, MT; Viola, RM; Forrest, JN (2013). "CGMP Inhibition of Type 3 Phosphodiesterase is the Major Mechanism by which C-type Natriuretic Peptide Activates CFTR in the Shark Rectal Gland". American Journal of Physiology. Cell Physiology. 306 (4): C343–C353. doi:10.1152/ajpcell.00326.2013. PMC 3919979. PMID 24259420.