Cibenzoline

Cibenzoline (or cifenline) is a Class Ia antiarrhythmic drug.[1][2]

Cibenzoline
Cibenzoline
Names
IUPAC name
2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.053.122 Edit this at Wikidata
KEGG
UNII
  • InChI=1/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20)
    Key: IPOBOOXFSRWSHL-UHFFFAOYAC
  • N\1=C(\NCC/1)C4CC4(c2ccccc2)c3ccccc3
Properties
C18H18N2
Molar mass 262.35 g/mol
Pharmacology
C01BG07 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cibenzoline (or cifenline) is a Class Ia antiarrhythmic drug.[1][2]

Pituxate & Ecipramidil are other gem-diphenyl cyclopropanyl drugs.

References

  1. ^ Harron, Dean W. G.; Brogden, Rex N.; Faulds, Diana; Fitton, Andrew (1992-05-01). "Cibenzoline". Drugs. 43 (5): 734–759. doi:10.2165/00003495-199243050-00008. ISSN 1179-1950.
  2. ^ Miura, Dennis S.; Keren, Gad; Torres, Vilma; Butler, Brenda; Aogaichi, Keiko; Somberg, John C. (1985-04-01). "Antiarrhythmic effects of cibenzoline". American Heart Journal. 109 (4): 827–833. doi:10.1016/0002-8703(85)90646-5. ISSN 0002-8703.


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