Charles McNeill Gray was born in Sherburne, New York on June 13, 1807.[3][4] He arrived in Chicago on July 17, 1834, and took a job as a clerk for Gurdon Saltonstall Hubbard, later working for Peter Cohen, a retail merchant. By 1844 he was a candle maker with his own shop. He subsequently worked as a manufacturer, contractor and railroad man.[5]He was elected mayor in 1853.
He died at his home in Chicago on October 17, 1885, and was buried at Graceland Cemetery.[3]