Mone was a member of the Michigan Wolverines for five seasons. He played in all 12 of Michigan's games as a true freshman, recording nine tackles (1.5 for loss), but missed his entire sophomore year after breaking his leg in preseason practice.[1] As a fifth-year senior, Mone made 13 tackles (1.5 for loss) with a half a sack was named honorable mention All-Big Ten Conference.[2] Mone finished his collegiate career with 43 tackles, 5.0 tackles for loss, two passes broken up and two fumble recoveries in 48 games played.[3]
Mone signed with the Seattle Seahawks as an undrafted free agent on April 28, 2019.[5] Mone made his NFL debut on September 8, 2019, against the Cincinnati Bengals, making three tackles.[6] He was waived on September 26, 2019, and re-signed to the practice squad.[7] He was released on October 23. He was added back to practice squad on October 29. He was promoted to the active roster on December 20.[8]
Mone re-signed with the Seahawks on April 23, 2020.[9] He was placed on injured reserve on November 14, 2020.[10] He was placed on the reserve/COVID-19 list by the team on December 5, 2020,[11] and moved back to injured reserve on December 16.[12] On December 26, 2020, Mone was activated off of injured reserve.[13]
On June 20, 2022, Mone signed a two-year contract extension with the Seahawks worth up to $12 million. He suffered a torn ACL in Week 15 and was placed on injured reserve on December 20, 2022.[15] He was placed on the reserve/physically unable to perform list to start the 2023 season.[16]
On March 6, 2024, Mone was released by the Seahawks.[17]